Hydroxypropyl beta cyclodextrinDetails : Hydroxypropyl beta cyclodextrin; HPBCD; HPCD CAS No.: 94035-02-6 M.F. :C42.(H)70-n.O35.(C3H7)n M.W. :1431-1806 Standards: USP40,EP9.0 Grade: Oral or Injection Storage:Preserved in well-closed containers Shelf life : 2 years when properly stored. Package:1kg/bag,25kg/drum.Or it's at your option. Introduction : Hydroxypropyl-β-cyclodextrin (HP-β-CD) is the hydroxyalkylated derivatives of β- cyclodextrin (β-CD). HP-β-CD is non-toxic and has no side effect, and it can significantly improve the solubility of insoluble drugs to dissolve insoluble or poorly water-soluble drugs due to its structural particularity. Therefore, it can effectively increase bioavailability of drugs; it can also improve drug quality and variety of dosage forms, thereby being applied in development and production of new drugs. Globally, in-depth studies of the properties, preparation technology, stability, pharmacology, toxicology, teratogenic, mutagenic, carcinogenic, hemolysis, irritation and other aspects of HP-β-CD have already been performed; the safety of this drug has been evaluated accurately. Among all the derivatives of β-CD, HP-β-CD is considered as a type of pharmaceutical excipients with most complete research data and highest medicinal value, and it has been studied in-width and in-depth mostly. Applications: 1:Medical use of hydroxypropyl β-cyclodextrin Due to the low surface activity, low hemolytic activity and non-irritation to muscles, Hydroxypropyl β-cyclodextrin is considered an ideal pharmaceutical excipient and solubilizer in injections in pharmaceutical industry. It works to solubilize water-insoluble drugs, enhance drug stability, improve drug bio-availability (improve efficacy or lower dosage of drugs), moderate and control drug release, and can also help to diminish the toxicity and side effects of drugs. Further, Hydroxypropyl β-cyclodextrin can be applied as a drug carrier in oral medications, injections, mucosal drug deliv
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